This blog is meant to give you a little information on AML cancer and treatment in All India Institute of Medical Science (AIIMS), Delhi, India under haematology department.
-Based on practical experience
MRD test is a new thing i heard in AML cases, yes it might be a common word for you, but at least this is not used in AIIMS
What is Minimum Residual Disease ( MRD ) test?
Progress in understanding DNA changes in AML has already provided a highly sensitive test for detecting the smallest amount of leukemia left after treatment (minimal residual disease), even when so few leukemia cells are present that they cannot be found by routine bone marrow tests.
The polymerase chain reaction (PCR) test can identify AML cells based on their gene translocations or rearrangements. This test can find one leukemia cell among a million normal cells. A PCR test can be useful in determining how completely the treatment has destroyed the AML cells.
Doctors are now trying to determine what effect minimal residual disease has on a patient's outlook, and how this might affect the need for further or more intensive treatment.